Linezolid-Associated Thrombocytopenia in Children With Renal Impairment.
نویسندگان
چکیده
Impaired renal function has been associated with an increased risk of thrombocytopenia in adults receiving linezolid. Findings from this retrospective cohort demonstrate an association between thrombocytopenia and lower creatinine clearance in children receiving linezolid.
منابع مشابه
Linezolid-related adverse effects in clinical practice in children.
INTRODUCTION Linezolid may cause adverse effects such as thrombocytopenia, which were found to be dependent on receiving linezolid for longer than 2 weeks. There are limited studies concerning the safety and timing of linezolid-related adverse effects in children. Objective of this study was to evaluate the incidence of adverse effects associated with linezolid, with especially focusing on the ...
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Linezolid is an antimicrobial agent to treat infections by Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). While effective, linezolid treatment frequently is associated with hematological side effects, especially thrombocytopenia. However, little is known about the mechanism of this side effect and the exposure-response relationship. The present population...
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ورودعنوان ژورنال:
- Journal of the Pediatric Infectious Diseases Society
دوره 4 3 شماره
صفحات -
تاریخ انتشار 2015